Research

Ordinary platelet gels contain minimal increases in platelet concentration. Pooled, human derived fibrin glue products contain no bioactive signal proteins. However, the concentrated platelets and white blood cells found in APC+ contain the bioactive proteins vital for initiating and accelerating tissue repair and regeneration:

Growth factors derived from platelets affect mitogenic activity of osteoblasts and other undifferentiated cells¹
At the wound site, the growth factors act on undifferentiated cells with respect to cell recruitment (chemoattraction) and cell division (mitosis)²
Concentration of platelets well above baseline levels not only increases the attraction of undifferentiated cells to the wound site but also proliferation of those cells³
The enhanced cellular proliferation resulting from high platelet concentrations can even allow for a reduction in autograft requirements as well as accelerate bone and soft tissue healing^4,5,6