Performance

As clinicians, it can be difficult to separate fact from fiction, but at Harvest, the proof is in the product. Unlike other systems, the SmartPReP 2 produces viable platelets increased 4x or greater above baseline levels.

The SmartPReP 2 produces the highest concentration of platelets, with the highest level of reproducibility, in the shortest time.

Performance Summary Platelet Gel Technology Platforms

Technology Platform	Increase Above Baseline 60 ml Process Volume		Coefficient of Variance, %
Technology Platform	7 ml PRP	10 ml PRP	Coefficient of Variance, %
Harvest SmartPRep 2^1,3	7.6x	4.6x	5.2%
Medtronic Magellan^2,3	5.1x	3.6x	8.9%
COBE Angel⁴	4.3x	3.0x	-
Fresenius CATS^1,3	3.4x	2.4x	16%
Biomet GPS ¹	3.2x	2.3x	21.0%
PPAI Sequire¹	2.0x	1.4x	48.0%

Technology Platform	Time to Process 120 ml of Whole Blood, min
Technology Platform	Operator	Process	Total
Harvest SmartPRep 2 ¹	2	14	16
Fresenius CATS¹	10	10	20
PPAI Sequire¹	10	12	22
COBE Angel ¹	3	22	25
Biomet GPS⁵	15	12	27
Medtronic^1,6 Magellan	3	30	33

¹Kevy, et al, Comparison of Methods for Point of Care Preparation of Autologous Platelet Gel, JECT, 2004; 36:28-35.

²Kevy, et al, Center for Blood Research; Presented at AMSECT - Hemostatis in Blood Management Meeting; April 2004

³Stammers, A.H., Trowbridge, C.C., et al, Establishment of a Quality Control Program for Platelet Gel Preparation: A Comparison of Four Commercial Devices - Society of Cardiovascular Anesthesiology Meeting: 9th Annual Update on Cardiopulmonary Bypass, March 2004

⁴Cobe Cardiovascular, Angel Whole Blood Separation, 2004 306700000 Rev A 10/04 5x increase in 10% of whole blood volume processed 5x in (0.10 x 60 ml) = 5x in 6 ml PRP

⁵ Cobe Cardiovascular, Angel Whole Blood Separation, 2004 306700000 Rev A 10/04 15 min to process 40 ml/28 minutes to process 180 ml Time to process 120 ml = 15 min + {(28 min -15 min)/(180 ml - 40 ml)} x 80 ml = 22.4 min

⁶Process times of 15.5 min per pass presented Sept 24, 2005, California State Perfusion Society Meeting, Lake Tahoe, NV.