Hematopoietic Stem Cells Regulate Mesenchymal Stromal Cell Induction into Osteoblasts Thereby Participating in the Formation of the Stem Cell Niche
This article from the August 2008 issue of Stem Cells provides the first evidence of a reciprocal cooperation between HSCs and the stem cell niche. It was determined that HSCs were responsible for direct mesenchymal differentiation toward osteoblastic lineage.
Comparison of Sternal, Iliac, and Humeral Bone Marrow Aspiration in Beagle Dogs
The sternum is known to be a suitable site for bone marrow aspiration; it is accessible (soft, with minimal soft tissue covering) and viable (hematopoiesis remains active throughout adulthood). However, surgeons have been deterred by the concern over thoracic injury when accessing the sternum. Researchers in this study performed bone marrow sternal aspiration with ordinary equipment and found it to be feasible and safe in small dogs under either general anesthesia or sedation.
A Prospective Comparison of 3 Approved Systems for Autologous Bone Marrow Concentration Demonstrated Nonequivalency in Progenitor Cell Number and Concentration
This 2014 publication reports the findings of a head-to-head evaluation of three bone-marrow processing (centrifugation) systems: the Harvest SmartPrep 2 BMAC, Biomet BioCUE, and Arteriocyte Magellan systems. Researchers measured progenitor cells both before and after centrifugation, via connective tissue progenitor (CTP) counts.
Comparative Analysis of Bone Marrow Concentrates Prepared by the Harvest®/Terumo System and the Cytomedix™/Angel® System
This 2013 comparative analysis evaluated two bone marrow centrifugation systems: the Harvest® SmartPrep 2 (Terumo BCT) and CytoMedix™ Angel® systems.
Comparison of Bone Marrow Concentrates Prepared by the Harvest/Terumo BMAC® System and the Thermogenesis Res-QT160 System
This 2012 comparative analysis evaluated two bone marrow centrifugation systems: the Harvest BMAC (Terumo BCT) and the Res-QT160 (Thermogenesis) systems.